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NSAIDs increase the risk of CVD in patients with osteoarthritis

KEY POINT

Results of an observational study published in Arthritis & Rheumatology showed that patients with osteoarthritis are at an increased risk for cardiovascular disease (CVD) compared with those who do not have the condition, and that NSAID use may play a substantial role in increasing this risk.

SOURCES

Atiquzzaman M, et al. Role of non-steroidal anti-inflammatory drugs (NSAIDs) in the association between osteoarthritis and cardiovascular diseases: A longitudinal study. Arthritis Rheumatol. 2019;[Epub ahead of print].

FDA. FDA drug safety communication: FDA strengthens warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) can cause heart attacks or strokes. www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-strengthens-warning-non-aspirin-nonsteroidal-anti-inflammatory. Accessed August 25, 2019.