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High-potency statins linked to acute kidney injury

April 26, 2013
  • Advising on this article:
  • Edward F. Foote

KEY POINT

Individuals taking high-potency statins (defined as daily dose of at least 10 mg rosuvastatin [Crestor—AstraZeneca], 20 mg atorvastatin, or 40 mg simvastatin) were more likely to be hospitalized for acute kidney injury within 120 days of starting treatment than low-potency statin users.

SOURCES

Dormuth CR et al. Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases. BMJ. 2013;346:f880. 

Fassett RG et al. Statins in acute kidney injury: friend or foe [editorial]? BMJ. 2013;346:f1531.

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