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Another negative trial for vitamin D supplementation

KEY POINT

Supplementation with high-dose vitamin D in older adults did not lower the incidence of invasive cancer or adverse cardiovascular (CV) events compared with placebo, according to results of the VITAL study published in the New England Journal of Medicine.

SOURCES

Manson JE, et al. Vitamin D supplements and prevention of cancer and cardiovascular disease. N Engl J Med. 2019;380(1):33–44.

Keaney JF, et al. VITAL signs for dietary supplementation to prevent cancer and heart disease. N Engl J Med. 2019;380(1):91–3. 

Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium, et al. Dietary reference intakes for calcium and vitamin D. Accessed January 29, 2019.