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Factors that may predict sustained efficacy after a short course of OTC PPIs

KEY POINT

Heartburn resolution within 7 days following completion of a 2-week course of OTC proton pump inhibitor (PPI) therapy (i.e., esomeprazole) was more common in patients who had less baseline heartburn frequency, in those who had symptom resolution during the last 7 days of treatment, and in patients who had the most heartburn-free days during the 2-week treatment period, according to results of a post-hoc analysis published in BMC Gastroenterology.