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Modest increase in creatinine after ACE inhibitor or ARB use associated with cardiorenal risks

KEY POINT

Elevations in serum creatinine in patients initiating angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) were associated with increased cardiorenal risks in a graduated fashion starting at creatinine increases of as low as 10%, according to results of a population-based cohort study published online in BMJ.