Focus on Anticoagulation Care

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Real-world outcomes of direct oral anticoagulants versus warfarin

KEY POINT

Apixaban (Eliquis—Bristol-Myers Squibb, Pfizer) appeared to be the safest direct oral anticoagulant compared with warfarin with respect to major, intracranial, and gastrointestinal bleeding, whereas rivaroxaban (Xarelto—Janssen) and low-dose apixaban were associated with an increased risk of all-cause mortality compared with warfarin, according to results of a prospective open cohort study published in BMJ.