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Metformin and the risk of acidosis in patients with kidney disease

KEY POINT

Use of metformin in patients with an estimated glomerular filtration rate (eGFR) between 30 mL/min/1.73 m2 and 45 mL/min/1.73 m2 did not result in an increased risk of incident acidosis compared with alternative diabetes treatments, according to data from two large retrospective cohort analyses.